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Volume-2 Issue-4, April 2018, ISSN: 2394-367X (Online)
Published By: Blue Eyes Intelligence Engineering & Sciences Publication Pvt. Ltd.

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1.

Authors:

Divya Sanganabhatla, R. Shyam Sunder, Harshit Malpani

Paper Title:

Introduction To Solid Lipid Nano Particles- An Overview

Abstract: Solid lipid nanoparticles are of major importance to the developing field of nano technology with applications in drug delivery, research and clinical medicine and other sciences. SLN dispersions have been proposed as a new type of colloidal drug carrier system suitable for intravenous administration. Solid lipid nanoparticles are submicron colloidal carriers composed of a single lipid core matrix that is solid at body temperature, and is coated with a surfactant acting as stabilizer. The conventional approaches such as use of permeation enhancers, surface modification, prodrug synthesis, complex formation and colloidal lipid carrier based strategies have been developed for the delivery of drugs to intestinal lymphatics. Aspects of solid lipid nanoparticles route of administration and their bio distribution are also incorporated. If appropriately investigated, solid lipid nanoparticles may open new vistas in therapy of complex diseases. It also discusses the potential of SLNs in brain targeting

Keywords: Nano Particles, Solid Lipid Nanoparticles (SLNs), TEM, PCS, Bio Distribution.

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