H.Pylori Related Peptic Ulcer Disease–Overview
Divya Sanganabhatla1, R. Shyam Sunder2

1Divya Sanganabhatla, Research Scholar, University College of Technology, Osmania University, Hyderabad (Telangana) -500007, India. 
2R. Shyam Sunder, Professor, University College of Technology, Osmania University, Hyderabad-500007, (Telangana), India.
Manuscript received on October 30, 2017. | Revised Version Manuscript Received on November 02, 2017 | Manuscript published on November 20, 2017. | PP: 8-12 | Volume-2 Issue-3, November 2017.
Open Access | Ethics and Policies | Cite
© The Authors. Published by Lattice Science Publication (LSP). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: H. pylori are spiral-shaped bacteria that grow in the digestive tract and have a tendency to attack the stomach lining. H. pylori infections are usually harmless, but they’re responsible for the majority of ulcers in the stomach and small intestine. H. pylori are adapted to live in the harsh, acidic environment of the stomach. These bacteria can change the environment around them and reduce its acidity so they can survive. The shape of H. pylori allows them to penetrate your stomach lining, where they’re protected by mucus and your body’s immune cells are not able to reach them. The bacteria can interfere with your immune response and ensure that they’re not destroyed. This can lead to stomach problems .These are diagnosed by various tests clinically. After H. pylori is identified in patients with gastritis or a peptic ulcer, the standard procedure is to eradicate the bacterial infection and allow the ulcer to heal. The typical therapy is a one week “triple therapy” consisting of a proton pump inhibitor such as omeprazole and the antibiotics clarithromycin and amoxicillin. There have been different varieties of the “triple therapy” that have been developed. Some varieties may use a different proton pump inhibitor such as pantoprazole or rabeprazole. They may also replace the amoxicillin with metronidazole for people who are allergic to penicillin. The new revolutions in therapy have made the treatment of peptic ulcers easier and have made it possible to cure the disease. In prior times only the symptoms were treated using antacids, H2-antagonists or proton pump inhibitors alone. Now further advancements have allowed for the treatment process to even decrease from 14 days to a possible 7-10 day treatment period. With advances in the efficacy of proton pump inhibitors a change in the patients diet is not even necessary
Keywords: Quadruple therapy; Stool test; Triple therapy; Urea breathe test.